Validation of a multimodal blood-based test for the detection of colorectal cancer with sub single molecule sensitivity
Blood-based colorectal cancer (CRC) screening tests can improve adherence to screening guidelines…
New ECLIPSE study validates the accuracy of Shield. See the data
06/03/2022
Blood-based colorectal cancer (CRC) screening tests can improve adherence to screening guidelines…
in real-world clinical settings for colorectal cancer (CRC) screening1*
Proven accuracy in the pivotal ECLIPSE† trial, with 83% sensitivity and 90% specificity2‡§
*Compliance rate for the first 8,000 patients that were prescribed Shield and completed it.1
†The ECLIPSE study (NCT04136002) is comparing the sensitivity and specificity of cfDNA only Shield with findings from subsequent colonoscopy in over 10,000 average-risk patients.1,2
‡Specificity detected for advanced neoplasia defined in ECLIPSE as CRC or advanced adenomas.1,3
§Patients had no prior diagnosis of CRC, inflammatory bowel disease, or family history of genetic risk for CRC (eg, Lynch syndrome).3
References: 1. Data on file. Guardant Health, Inc. 2. Guardant Health press release. December 15, 2022. 3. ECLIPSE trial on ClinicalTrials.gov
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