Guardant Health announces positive results from pivotal ECLIPSE study evaluating a blood test for the detection of colorectal cancer
Study demonstrates 83% sensitivity for detection of colorectal cancer with specificity of 90%
Review the ECLIPSE study published in New England Journal of Medicine. See the data
12/15/2022
Study demonstrates 83% sensitivity for detection of colorectal cancer with specificity of 90%
in real-world clinical settings for colorectal cancer (CRC) screening1*
Proven accuracy in the pivotal ECLIPSE† trial, with 83% sensitivity and 90% specificity2‡§
*Compliance rate for the first 8,000 patients that were prescribed Shield and completed it.1
†The ECLIPSE study (NCT04136002) is comparing the sensitivity and specificity of cfDNA only Shield with findings from subsequent colonoscopy in over 10,000 average-risk patients.1,2
‡Specificity detected for advanced neoplasia defined in ECLIPSE as CRC or advanced adenomas.1,3
§Patients had no prior diagnosis of CRC, inflammatory bowel disease, or family history of genetic risk for CRC (eg, Lynch syndrome).3
References: 1. Data on file. Guardant Health, Inc. 2. Guardant Health press release. December 15, 2022. 3. ECLIPSE trial on ClinicalTrials.gov
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